Single-stranded, adenine-rich RNA from purified reoviruses.

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Single-stranded, adenine-rich RNA from purified reoviruses.

Reoviruses are known to contain double-stranded (DS) RNA.' It was therefore surprising to find that RNA extracted from highly purified reovirus type 3 and analyzed without further fractionation had a purine/pyrimidine ratio of 1.5 and an adenylic acid content of more than 40 moles per cent. In an effort to understand the basis for this observation, the RNA's of all three reovirus serotypes were...

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Single-stranded adenine-rich DNA and RNA retain structural characteristics of their respective double-stranded conformations and show directional differences in stacking pattern.

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Absence of adenine-rich ribonucleic acid from purified infectious reovirus 3.

The basic properties of released and cell-associated reovirus are the same. Both contained as their total nucleic acid complement only double-stranded ribonucleic acid (RNA) with an adenine content of 28%. Preparations of purified cell-associated virus, but not released virus, contained adenine-rich RNA which could be separated from the virus with little or no loss of infectivity. These adenine...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1968

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.59.1.246